Cruise Results

Cruises Found: 113

Sort: Price | Departure Date | Length

7-night Southern Caribbean Cruise

OFFER ID 1564638

Select

Supplier:

Royal Caribbean International®

Ship:

Serenade of the Seas

Destination:

Roundtrip Colon (Panama)

Dates:

02/07/2026

Length:

7 Days

from $1613

7-night Southern Caribbean Cruise

OFFER ID 1564639

Select

Supplier:

Royal Caribbean International®

Ship:

Serenade of the Seas

Destination:

Roundtrip Colon (Panama)

Dates:

01/24/2026

Length:

7 Days

from $1459

7-night Southern Caribbean Holiday Cruise

OFFER ID 1564640

Select

Supplier:

Royal Caribbean International®

Ship:

Serenade of the Seas

Destination:

Roundtrip Colon (Panama)

Dates:

12/27/2025

Length:

7 Days

from $2623

7-night Panama And Costa Rica By Sea Cruise: The Natural Wonders Of Central America – With Smithsonian Journeys

OFFER ID 1566201

Select

Supplier:

PONANT EXPLORATIONS

Ship:

Le Champlain

Destination:

Colon (Panama)/Puntarenas

Dates:

02/19/2026

Length:

7 Days

from $6790

10-night Secrets Of Central America Cruise

OFFER ID 1566203

Select

Supplier:

PONANT EXPLORATIONS

Ship:

Le Champlain

Destination:

Colon (Panama)/Puntarenas

Dates:

01/19/2026

Length:

10 Days

from $10170

10-night Secrets Of Central America Cruise

OFFER ID 1566204

Select

Supplier:

PONANT EXPLORATIONS

Ship:

Le Champlain

Destination:

Colon (Panama)/Puntarenas

Dates:

03/05/2026

Length:

10 Days

from $10170

12-night Panama, Colombia & Caribbean Islands Cruise

OFFER ID 1566206

Select

Supplier:

PONANT EXPLORATIONS

Ship:

Le Champlain

Destination:

Colon (Panama)/Fort De France

Dates:

03/25/2026

Length:

12 Days

from $8940

7-night Enchanting Colombia And Panamanian Islands Cruise

OFFER ID 1595302

Select

Supplier:

Windstar Cruises

Ship:

Wind Spirit

Destination:

Colon (Panama)/Oranjestad, Aruba

Dates:

12/13/2025

Length:

7 Days

from $3115

15-night Star Collector: Panama Canal, Costa Rica & Mexican Riviera Discovery Cruise

OFFER ID 1595373

Select

Supplier:

Windstar Cruises

Ship:

Star Seeker

Destination:

Colon (Panama)/Puerto Vallarta

Dates:

04/13/2026

Length:

15 Days

from $9978

7-night Central America Jewels & Panama Canal Cruise

OFFER ID 1597918

Select

Supplier:

PONANT EXPLORATIONS

Ship:

Le Dumont-D'Urville

Destination:

Colon (Panama)/Puntarenas

Dates:

12/19/2025

Length:

7 Days

from $5810

7-night Central America Jewels & Panama Canal Cruise

OFFER ID 1597920

Select

Supplier:

PONANT EXPLORATIONS

Ship:

Le Dumont-D'Urville

Destination:

Colon (Panama)/Puntarenas

Dates:

01/02/2026

Length:

7 Days

from $5810

12-night Panama, Colombia & Caribbean Islands Cruise

OFFER ID 1597922

Select

Supplier:

PONANT EXPLORATIONS

Ship:

Le Dumont-D'Urville

Destination:

Colon (Panama)/Fort De France

Dates:

01/16/2026

Length:

12 Days

from $8480

10-night Panama Canal Westward Cruise

OFFER ID 1607104

Select

Supplier:

Royal Caribbean International®

Ship:

Serenade of the Seas

Destination:

Colon (Panama)/Los Angeles

Dates:

04/25/2026

Length:

10 Days

from $1041

1-night Southern Caribbean Cruise

OFFER ID 1607105

Select

Supplier:

Royal Caribbean International®

Ship:

Serenade of the Seas

Destination:

Colon (Panama)/Cartagena (Colombia)

Dates:

04/18/2026

Length:

1 Days

from $140

6-night Panama’s Pristine Caribbean Cruise

OFFER ID 1618180

Select

Supplier:

Windstar Cruises

Ship:

Star Pride

Destination:

Colon (Panama)/Oranjestad

Dates:

03/09/2026

Length:

6 Days

from $2519

7-night Costa Rica & Panama Canal Cruise

OFFER ID 1618210

Select

Supplier:

Windstar Cruises

Ship:

Wind Star

Destination:

Colon (Panama)/Puerto Caldera (Puntarenas)

Dates:

12/05/2026

Length:

7 Days

from $4569

7-night Costa Rica & Panama Canal Cruise

OFFER ID 1618214

Select

Supplier:

Windstar Cruises

Ship:

Wind Star

Destination:

Colon (Panama)/Puerto Caldera (Puntarenas)

Dates:

12/19/2026

Length:

7 Days

from $3769

7-night Costa Rica & Panama Canal Cruise

OFFER ID 1618228

Select

Supplier:

Windstar Cruises

Ship:

Wind Star

Destination:

Colon (Panama)/Puerto Caldera (Puntarenas)

Dates:

01/02/2027

Length:

7 Days

from $4169

10-night Monteverde Cloud Forest & Arenal Volcano Cruise/Land Package

OFFER ID 1623649

Select

Supplier:

Windstar Cruises

Ship:

Wind Star

Destination:

Colon (Panama)/San Jose (C.R.)

Dates:

12/05/2026

Length:

10 Days

from $6969

10-night Monteverde Cloud Forest & Arenal Volcano Cruise/Land Package

OFFER ID 1623852

Select

Supplier:

Windstar Cruises

Ship:

Wind Star

Destination:

Colon (Panama)/San Jose (C.R.)

Dates:

12/19/2026

Length:

10 Days

from $6169

10-night Monteverde Cloud Forest & Arenal Volcano Cruise/Land Package

OFFER ID 1623853

Select

Supplier:

Windstar Cruises

Ship:

Wind Star

Destination:

Colon (Panama)/San Jose (C.R.)

Dates:

01/02/2027

Length:

10 Days

from $6569

10-night Secrets Of Central America Cruise

OFFER ID 1626302

Select

Supplier:

PONANT EXPLORATIONS

Ship:

Le Bellot

Destination:

Colon (Panama)/Puntarenas

Dates:

11/21/2026

Length:

10 Days

from $9010

12-night Panama, Colombia & Caribbean Islands Cruise

OFFER ID 1626309

Select

Supplier:

PONANT EXPLORATIONS

Ship:

Le Bellot

Destination:

Colon (Panama)/Fort de France

Dates:

03/29/2027

Length:

12 Days

CALL

10-night Secrets Of Central America Cruise

OFFER ID 1626329

Select

Supplier:

PONANT EXPLORATIONS

Ship:

Le Laperouse

Destination:

Colon (Panama)/Puntarenas

Dates:

12/19/2026

Length:

10 Days

from $8530

7-night Central America Jewels & Panama Canal Cruise

OFFER ID 1626332

Select

Supplier:

PONANT EXPLORATIONS

Ship:

Le Laperouse

Destination:

Colon (Panama)/Puntarenas

Dates:

01/15/2027

Length:

7 Days

from $5980

Prev Next

Modify Cruise Search

To select multiple options, hold the CTRL-key. (CMD on Mac)

Between

And

Display only offers with pricing

Signature Collection

Reset

CRUISE SEARCH CRUISE ADVANCED SEARCH CRUISE LINES DESTINATIONS SIGNATURE COLLECTION CRUISE PORTS